Cone Health System

Impact of a multi-hospital intervention utilising screening, hand hygiene education and pulsed pxenon ultraviolet (PX-UV) on the rate of hospital associated meticillin resistant Staphylococcus aureus infection.

Simmons S, Morgan M, Hopkins T, Helsabeck K, Stachowiak J, Stibich M; Journal of Infection Prevention 2013, 14:172-174.

Standard approaches to meticillin resistant Staphylococcus aureus (MRSA) prevention have included hand hygiene and active surveillance. These approaches have shown mixed results. The addition of pulsed xenon ultraviolet (PX-UV) room disinfection for MRSA prevention is a novel approach. This new MRSA prevention method was implemented at an acute care hospital system in Greensboro, NC, USA. An MRSA screening programme was implemented over a six-month period from July 2011 to January 2012 to include all high-risk patients and the majority of surgical patients. A two-week hand hygiene education initiative was implemented in February 2011. The use of PX-UV for terminal cleaning of MRSA patient rooms was also implemented in February 2011. The rates of hospital associated MRSA (HA-MRSA) infections were monitored before and after implementation of all prevention efforts. The HA-MRSA rate decreased at the largest facility in the system by 57%, and for the entire healthcare system by 56% (p=0.001). The two smaller hospitals saw reductions of 51% and 66%, but the results were not statistically significant (p=0.1047 and p=0.2263). Implementing a PX-UV device in conjunction with active screening and hand hygiene was associated with a decrease in HA-MRSA rates. Studies on the individual effect of PX-UV on HA-MRSA rates are warranted.